Can phenytoin cause anemia

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August undefined, 2024

WebSep 20, 2024 · Hemodialysis can also cause iron deficiency anemia. One study showed that patients receiving hemodialysis may lose up to 2 g of iron per year. Pregnancy can also cause iron stores to be low. During pregnancy, the body produces more red blood cells to support the developing fetus, which uses up the mother’s iron stores. WebJan 4, 2024 · Symptoms. Initially, iron deficiency anemia can be so mild that it goes unnoticed. But as the body becomes more deficient in iron and anemia worsens, the signs and symptoms intensify. Iron deficiency anemia signs and symptoms may include: Extreme fatigue. Weakness. Pale skin.

Phenytoin (Oral Route) Side Effects - Mayo Clinic

WebDrugs such as methotrexate, phenytoin, sulfasalazine, and trimethoprim can antagonize folate utilization, inhibit its absorption or conversation to its active form resulting in folate deficiency 151). Congenital deficiencies of enzymes required in folate metabolism can lead to folate deficiency. ... and both cause megaloblastic anemia, ... WebDiphenylhydantoin (Dilantin) has been used extensively as anticonvulsant therapy since its introduction in 1938, as has phenobarbital since 1912. It was not until 1952 that Mannheimer et al. 1 described leukopenia and megaloblastic anemia in an epileptic patient being treated with diphenylhydantoin. fisher class terraria

Megaloblastic Anemia During Anticonvulsant Drug Therapy - JAMA

WebPhenytoin, particularly in high dosages, may cause hyperglycemia by inhibiting insulin release. The drug may also raise serum glucose levels in diabetic patients. Therapy with phenytoin should be administered cautiously in patients with diabetes mellitus, glucose intolerance, or a predisposition to hyperglycemia. WebJul 19, 2006 · AED use was more prevalent among cases (9.2%) than among controls (0.8%). After adjustment for confounders, the use of AEDs was significantly associated with aplastic anemia (adjusted odds ratio (OR), 9.5; 95% confidence interval (CI), 3.0–39.7). The most frequently used AEDs were carbamazepine (CBZ), valproic acid (VPA), and … WebCauses of this type of anemia include: Too little folic acid in your diet; Hemolytic anemia; Long-term alcoholism; Use of certain medicines (such as phenytoin [Dilantin], methotrexate, sulfasalazine, triamterene, pyrimethamine, trimethoprim-sulfamethoxazole, and barbiturates) The following raise your risk for this type of anemia: Alcoholism fisher cleanroom cleaning

Diagnosis and treatment of macrocytic anemias in adults

Could my medication have caused anemia? - MedHelp

WebApr 13, 2024 · 1 Introduction. Anemia is one of the most commonly diagnosed conditions by primary care physicians. In 2010, global anemia prevalence was 32.9%, that is, more than 2.2 billion people were … WebPhenytoin is frequently used anticonvulsant, rarely it may be related to serious complication such as aplastic anemia. [ 9] Routine monitoring of complete blood count helps to … canada world cup games live streamWebJan 1, 2009 · Drug-induced immune hemolytic anemia (DIIHA) is rare. The incidence of drug-induced immune thrombocytopenia and neutropenia is quite well documented (10 to 18 and 2 to 15 cases per million, respectively), 1, – 3 but there are no good data for DIIHA. We have roughly estimated it to be around 1 in 1 million of the population, by comparing it to … fisher clearance

"WebPhenytoin can cause the platelet or white blood cell counts to drop, increasing the risk of bleeding or infection, respectively. Phenytoin also can cause anemia . Because it … " - Can phenytoin cause anemia

Can phenytoin cause anemia

WebAnemia can be caused by many conditions, including loss of blood during heavy menstruation, pregnancy, blood donation, bleeding ulcers, chronic heart failure, and surgery (before and after). There is also a type of anemia called anemia of chronic disease, which can occur in people with chronic kidney failure and those undergoing chemotherapy. WebUse of certain medicines (such as phenytoin [Dilantin], methotrexate, sulfasalazine, triamterene, pyrimethamine, trimethoprim-sulfamethoxazole, and barbiturates) ... Symptoms of anemia can cause discomfort. In pregnant women, folate deficiency has been associated with neural tube or spinal defects (such as spina bifida) ...

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WebApr 1, 2024 · This medicine may cause serious allergic reactions, including angioedema, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you or your child have large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs after using this medicine.

WebThe nutrient-drug interaction between folate and phenytoin is a two-way interaction. Folate deficiency resulting from long-term phenytoin therapy is a common occurrence, but progression of the deficiency to a megaloblastic anemia is rare. However, there are data to suggest nonanemic folate deficiency may be detrimental to the patient. Webepileptic patients, ASMs can cause anemia. Folic acid can be given to carbamazepine-treated anemic patients. There is growing evidence that it improves hemoglobin and leukocytes in individuals who take it. ... cases of aplastic anemia were described as well with phenytoin, valproate, and ethosuximide through interference with deoxyribonucleic ...

WebOct 22, 2015 · Phenytoin and other anticonvulsant agents have also been associated with the development of megaloblastic anemia. However, a … WebApr 13, 2024 · Megaloblastic anemia is caused by deficiency or impairment of utilization of vitamin B12 or folate. Nonmegaloblastic anemia may be the result of liver dysfunction, alcoholism, myelodysplastic syndrome (MDS), or hypothyroidism. Common causes of macrocytosis are different by region and setting.

WebDrugs that can cause this type of hemolytic anemia include: Cephalosporins (a class of antibiotics), most common cause; Dapsone; Levodopa; Levofloxacin; Methyldopa; …

WebSep 20, 2024 · Medications can cause vitamin deficiencies, including antibiotics, antacids, metformin (antidiabetic) and phenytoin (antiseizure). Tapeworm infections can lead to … canada world juniors finalWebMegaloblastic anemia is a type of macrocytic anemia.An anemia is a red blood cell defect that can lead to an undersupply of oxygen. Megaloblastic anemia results from inhibition of DNA synthesis during red blood cell … canada world junior scoreWebAnemia in liver disease can be due to many causes. Macrocytic anemia could be due to lack of vitamin B12 or folic acid which could be due to nutritional causes. Low transferrin can be due to poor production of transferrin by the liver, due to liver disease or excessive loss of transferrin through the kidneys into the urine. canada world juniors schedule 2013WebApr 14, 2024 · Taking warfarin with phenytoin can increase the level of phenytoin in your body. This may lead to more side effects. Also, phenytoin can affect how the body … canada world cup schedule 2022 qatar vsWebA 53-yr-old man sequentially developed aplastic anemia from phenytoin and carbamazepine. Both compounds undergo metabolism to potentially toxic arene oxide … fisher clifford b npiWebAntiepileptic drugs carbamazepine, phenytoin, and valproic acid induced aplastic anemia occurs via toxic metabolites. 11–13 The risk of aplastic anemia ranging from 1.4 to 60 cases/million, was detected among users of carbamazepine (within a 5-month period). 14 Felbamate proved to be a risk factor for aplastic anemia with an incidence of 127 ... canada world juniors hockeyWebPhenytoin may cause swelling and bleeding of the gums. ... (including liver disease caused by past phenytoin use), lupus, folate or vitamin B-12 deficiency (megaloblastic anemia). ... canada world juniors final game