WebMay 1, 2008 · Cisplatin is one of the most widely used and most potent chemotherapy drugs. However, side effects in normal tissues and organs, notably nephrotoxicity leading to tubular and inflammation. Renoprotective approaches are being discovered, but the protective effects are mostly partial, suggesting the need for combinatorial strategies. WebJul 22, 2024 · It is important to note that for many malignancies, cisplatin is used in combination with other drugs that may also be nephrotoxic. Cellular toxicity — Cisplatin (cis-diamminedichloroplatinum II [CDDP]), a platinum compound that is predominantly …
Myo-Inositol Supplementation Alleviates Cisplatin-Induced Acute …
WebOct 6, 2016 · Cisplatin [Cis-diamminedichloroplatinum (II)] is the most nephrotoxic chemotherapeutic drug, discovered over four decades ago. Nephrotoxicity is the major side effect that limits the dose of cisplatin that can be safely administered, and it is a clinical problem in cancer patients who receive cisplatin combination chemotherapy. WebJul 7, 2007 · Despite the clinical effectiveness of cisplatin as an anti-tumour drug, its nephrotoxic side effect has significantly restricted its use. In spite of prophylactic … flower technical drawing
Cisplatin Nephrotoxicity: A Review - Neil Kurtzman
WebNational Center for Biotechnology Information WebSide effect and toxicity management Prophylaxis and treatment Prevention and management of cisplatin nephrotoxicity ID: 184 v.3 Endorsed This document is an … WebNephropathy can be associated with some therapies used to treat cancer. The most common form of kidney disease in cancer patients is Acute Kidney Injury (AKI) which can … flower teas types