WebAug 15, 2010 · Recently, label-free technology platforms based on dynamic mass redistribution of intracellular proteins such as the Corning Epic Biosensor (for operating … WebAug 30, 2024 · The Nociceptin/Orphanin FQ (N/OFQ) peptide NOP receptor is coupled to pertussis toxin (PTX)-sensitive G proteins (Gi/o) whose activation leads to the inhibition of both cAMP production and calcium channel activity, and to the stimulation of potassium currents. The label free dynamic mass redistribution (DMR) approach has been …
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WebOct 23, 2011 · Independently, a cellular dynamic mass redistribution (DMR) assay had been developed to investigate cellular signaling pathways, especially GPCR-mediated transduction processes, with the ... WebLabel-free dynamic mass redistribution functional responses, however, revealed diverging effects of the PDZ ligand. While no clear trend was observed across all GPCRs tested or even within receptor families, a subset of GPCRs displayed diminished agonist efficacy in the absence of a PDZ ligand (i.e. HT2RB, ADRB1), whereas others demonstrated ... how to store leaf lettuce
Applying label-free dynamic mass redistribution technology to …
WebAug 15, 2010 · Recently, label-free technology platforms based on dynamic mass redistribution of intracellular proteins such as the Corning Epic Biosensor (for operating principle see Fig. 1a) or alteration of ... WebMar 1, 2008 · Dynamic mass redistribution (DMR) assays provide real-time, labelfree detection of stimulus-driven cellular responses [58, 59]. DMR responses are produced by changes in local refractive index ... WebThe Donnan redistribution should be considered to be a dynamic process advancing in the gel column with the zone of M and it should not be observable by means other than altered mass transport outside the column. Fig. 12 illustrates the situation. Fig. 12A shows conditions near the outlet of an ideal column when equilibriun is attained. read young and the restless fanfiction