Phesgo loading dose

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August undefined, 2024

WebJan 1, 2024 · − Phesgo 1200 mg (P)/600 mg (T)/30,000 units (hyu) single-dose vial: 1 vial as initial dose − Phesgo 600 mg (P)/600 mg (T)/20,000 units (hyu) single-dose vial: 1 vial … Web• The initial dose of PHESGO is 1,200 mg pertuzumab, 600 mg trastuzumab, and 30,000 units hyaluronidase administered subcutaneously over approximately 8 minutes, followed …

Getting the PHESGO injection

WebPHESGO is administered by slowly injecting it just under the skin of the thigh. At each appointment, the injection alternates between the left and right thigh. Injection time The first dose of PHESGO takes about 8 minutes to inject. Other doses take about 5 minutes to inject. WebPHESGO—a combination with PERJETA® (pertuzumab) & Herceptin® (trastuzumab) in a single ~5 minute injection under the skin.* *Your first dose is given in ~8 minutes. This … grons to go up

PHESGO® (pertuzumab / trastuzumab / hyaluronidase-zzfx) A …

WebMar 18, 2024 · The loading dose and maintenance dose should be administered over 8 and 5 minutes, respectively. An observation period of 30 minutes after completion of Phesgo … WebLoading (initial) dose. 1200 mg pertuzumab, 600 mg trastuzumab, 30,000 units hyaluronidase per 15 mL supplied in a single-dose, ready-to-use vial. Administer subcutaneously over approximately 8 minutes at a rate of no more than 2 mL/min. Treatment regimens for early and metastatic breast cancer, based on … Printable Resources - Dosing & Administration PHESGO® (pertuzumab … Side Effects - Dosing & Administration PHESGO® (pertuzumab / trastuzumab ... Practice Support Services - Dosing & Administration PHESGO® (pertuzumab … Trial Information - Dosing & Administration PHESGO® (pertuzumab / trastuzumab ... WebTable 2: Switching from intravenous pertuzumab and trastuzumab administration to Phesgo® Time since last dose Dose of Phesgo® <6 weeks Administer as a maintenance dose of 600 mg pertuzumab/600 mg trastuzumab and every 3 weeks for subsequent administrations ≥6 weeks Administered as a loading dose of 1200 mg pertuzumab/600 … grontheim valley vigor troll

PHESGO Breast Cancer Billing Codes - genentech-access.com

Getting the PHESGO injection

Web<6 weeks The maintenance dose of pertuzumab/trastuzumab (Phesgo®) 600 mg/600 mg should be administered as soon as possible. Thereafter, continue with the 3-weekly schedule. ≥6 weeks A loading dose of pertuzumab/trastuzumab (Phesgo®) 1200 mg/600 mg should be re-administered followed by maintenance dose of pertuzumab/trastuzumab … WebEBC & MBC Loading dose: 1,200 mg/600 mg trastuzumab given for approx 8 min. Maintenance dose: 600 mg/600 mg trastuzumab given for approx 5 min. Patients receiving taxane Administer treatment prior to taxane. Recommended initial dose … gron thc pearlsWeb• less than 6 weeks, the maintenance dose of Phesgo 600 mg/600 mg should be administered as soon as possible. Thereafter, continue with the 3-weekly schedule. • 6 … files to check in .project file ccs

"WebPregnant cynomolgus monkeys were treated on Gestational Day (GD) 19 with loading doses of 30 to 150 mg/kg pertuzumab, followed by bi-weekly doses of 10 to 100 mg/kg. ... " - Phesgo loading dose

Phesgo loading dose

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WebNov 13, 2024 · SC administration of Phesgo takes approximately eight minutes for the initial loading dose and approximately five minutes for each subsequent maintenance dose. 1 This is compared to approximately ... WebOct 13, 2024 · When administered with PHESGO, the recommended initial dose of docetaxel is 75 mg/m 2 administered as an intravenous infusion. The dose may be escalated to 100 mg/m 2 administered every 3 weeks if the initial dose is well tolerated. Administer PHESGO until disease progression or unmanageable toxicity, whichever occurs first. Dose …

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WebPhesgo has different dosage and administration instructions than IV pertuzumab, IV trastuzumab, and SC trastuzumab when administered alone. Do not substitute Phesgo for … WebInjected subcutaneously by a healthcare professional into the patient’s thigh Alternate between left and right thighs and allow 2.5 cm between previous injection site. Look for …

WebPhesgo will be administered subcutaneously (SC) at a fixed non-weight-based dose. In the induction therapy phase, a loading dose (1200 milligram (mg) pertuzumab, 600 mg trastuzumab, and 30,000 units of recombinant human PH20 hyaluronidase [rHuPH20]) will be administered in the first cycle (1 cycle is 21 days). WebPertuzumab/trastuzumab/hyaluronidase, sold under the brand name Phesgo, is a fixed-dose combination medication to treat adults with HER2-positive breast cancer that has spread to other parts of the body, and for treatment of adults with early HER2-positive breast cancer. [4] [5] It contains pertuzumab, trastuzumab, and hyaluronidase–zzxf. [4]

WebJun 29, 2024 · Today, the U.S. Food and Drug Administration approved Phesgo—a combination of pertuzumab, trastuzumab and hyaluronidase–zzxf—for injection under the skin to treat adult patients with... WebMar 1, 2024 · PHESGO comes in the following dosage forms: Loading dose: Sterile solution in a 20 mL vial containing 1200 mg pertuzumab ( 80 mg/mL) and 600 mg trastuzumab (40 mg/mL). Maintenance dose: Sterile solution in a15 mL vial containing 600 mg pertuzumab (60 mg/mL) and 600 mg trastuzumab (60 mg/mL). Do not use PHESGO if:

WebJul 1, 2024 · Phesgo takes about eight minutes to be administered for the initial loading dose, and about five minutes for subsequent doses. Phesgo’s approval was based on data from the FeDeriCa Phase 3 trial ( NCT03493854 ), whose goal was to directly compare the original Herceptin-Perjeta combination to Phesgo.

WebJan 1, 2024 · For CMS billing purposes, there are 1,800 mg of combined pertuzumab and trastuzumab in the loading dose (180 units) and 1,200 mg of combined pertuzumab and trastuzumab in the maintenance dose (120 units). Individual payers may have different preferences for billing PHESGO. Check with your local payers for specific information. gron trtfWebNov 16, 2024 · When administered with PHESGO, the recommended initial dose of docetaxel is 75 mg/m 2 administered as an intravenous infusion. The dose may be escalated to 100 … gronsky\u0027s milk house high bridge njWebJun 29, 2024 · The recommended initial dose of PHESGO is 1,200 mg pertuzumab, 600 mg trastuzumab, and 30,000 units hyaluronidase administered subcutaneously over approximately 8 minutes, followed every 3 weeks ... gronwall inequality intuition